It’s 11:11!

neurosciencestuff:

Pay attention: How we focus and concentrate

Scientists at Newcastle University have shed new light on how the brain tunes in to relevant information.

Publishing in Neuron, the team reveal the interplay of brain chemicals which help us pay attention in work funded by the Wellcome Trust and BBSRC.

By changing the way neurons respond to external stimuli we improve our perceptual abilities. While these changes can affect the strength of a neuronal response, they can also affect the fidelity of that response.

Lead author Alex Thiele, Professor of Visual Neuroscience explains: “When you communicate with others, you can make yourself better heard by speaking louder or by speaking more clearly. Neurons appear to do similar things when we’re paying attention. They send their message more intensely to their partners, which compares to speaking louder. But more importantly, they also increase the fidelity of their message, which compares to speaking more clearly.

“Our earlier work has shown that attention is able to affect the intensity of responses – in effect the loudness - by means of the brain chemical acetylcholine. Now we have shown that the fidelity of the response is altered by a different brain chemical system.”

In the paper, the team reveal that the quality of the response is altered by means of glutamate coupling to NMDA receptors (a molecular device that mediates communication between neurons). Carried out in a primate model, these studies for the first time isolate different attention mechanisms at the receptor level.

The research builds on the team’s previous studies and has potentially significant implications not only for our understanding of how our brains work but also give an insight into conditions such as schizophrenia, Alzheimer’s disease and attention deficit disorder, and may aid in the development of treatments for them.

(Source: verticalfood)

I am overwhelmed by Samuel Larson photos and my friends trying to figure out how the hell to play Risk.

4, 23, 33!
A:

4. Is there a color shirt you’d NEVER wear?

I’m pretty open, unless it was just a generally gross color. I dunno!

I’ve already answered 23 and 33 :)

Are there any really quality Glee HSM AU’s out there?

 #this is something I need in my life  #glee  #fanfiction
 #pretty  #san francisco

literaryreference:

You know how it is, right, ladies? You know a guy for a while. You hang out with him. You do fun things with him—play video games, watch movies, go hiking, go to concerts. You invite him to your parties. You listen to his problems. You do all this because you think he wants to be your friend.

But then, then comes the fateful moment where you find out that all this time, he’s only seen you as a potential girlfriend. And then if you turn him down, he may never speak to you again. This has happened to me time after time: I hit it off with a guy, and, for all that I’ve been burned in the past, I start to think that this one might actually care about me as a person. And then he asks me on a date.

I tell him how much I enjoy his company, how much I value his friendship. I tell him that I really want to be his friend and to continue hanging out with him and talking about our favorite books or exploring new restaurants or making fun of avant-garde theatre productions. But he rejects me. He doesn’t answer my calls or e-mails; if we’d been making plans to do something before this fateful incident, these plans mysteriously fail to materialize. (This is why I never did get around to seeing the Hunger Games movie. Not to name any names, but thanks a lot, Tom.) Later, when I run into him at social events, our conversations are awkward and lukewarm. This is because the moment we met, he put me in the girlfriend-zone, and now he can’t see me as friend material.

I must say that I find this really unfair. I mean, I’m a nice girl. I have a lot to offer as a friend, like not being a douchebag and stuff. But males just don’t want to be friends with nice girls like me. They can’t help it, I guess; it’s just how they’re wired, biologically. Evolution conditioned our male hominid ancestors to seek nice girls as mates and form friendship bonds only with the other dudes that they hunted mammoths with. It’s true—I know this because I studied hominids in my fifth-grade science class.

So what’s the answer? Should I take up mammoth-hunting in an attempt to appeal to the friendship centers of men’s primal lizardbrains? Should I keep making guy “friends” and then prevent them from making a move on me by subtly undermining their self-confidence? Should I just give up on those manipulative, game-playing, two-faced bastards once and for all? I don’t know. I mean, I’d really like to have a true friendship with a guy someday, but it’s so hard to trust and respect them when they never say what they mean—and you never know when you might be relegated to the girlfriend-zone.

 #feminism  #this is wonderful

Read More

 #read more
 #the great gatsby

Read More

 #read more  #please ignore my irrational emotional breakdown
 #darren criss

fear3loathing:

hipsterinatardis:

I need a Wallace Wells in my life because everyone needs a Wallace Wells in their life.

(Source: krevlornswath)

 #scott pilgrim  #wallace wells

blackshirtfistbump:

Do you ever get weirdly jealous when people you really like get affectionate anon messages from someone that isn’t you?

 #that is my person stay away from them other nice people
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